Emodepside for Trichuris trichiura and Hookworm Infection

Previous therapies against the human whipworm Trichuris trichiura and hookworms show poor and suboptimal efficacy, respectively, after a single dose. In the recent publication in the New England Journal of Medicine by Prof. Jenny Keiser, a phase 2 clinical study in Tanzania showed that a single dose of emodepside has excellent efficacy against whipworm even at low doses and also against hookworms at higher doses. Treatment with emodepside was generally well tolerated. The study was reported in an article on Deutschlandfunk and commented on by Prof. Hörauf, Prof. Hübner and Prof. Ramharter.